ZOSTRIX®
Medicis
Capsaicin
Neuralgia Therapy
Action And Clinical Pharmacology: Although the precise mechanism of action of capsaicin is not fully understood, current evidence suggests that capsaicin renders skin insensitive to pain by depleting and preventing reaccumulation of substance P in peripheral sensory neurons. Substance P is thought to be the principal chemomediator of pain impulses from the periphery to the CNS.
Indications: For the temporary relief of the pain (neuralgia) associated with and following episodes of herpes zoster infections after open skin lesions have healed. For the temporary relief of arthritic pain in rheumatoid and osteoarthritis.
Warnings: For external use only. Avoid contact with eyes and broken or irritated skin. Do not bandage. If condition worsens, or if symptoms persist for more than 14 days or clear up and occur again within a few days, discontinue use of this product and consult your physician. Keep this and all drugs out of the reach of children.
Dosage And Administration: Adults and children 2 years of age or older: Apply cream lightly to affected area not less than 3 or 4 times daily. It may cause transient burning on application. This burning is observed more frequently when application schedules of less than 3 or 4 times daily are utilized. After the cream is applied with the fingers, unless treating hands, the hands should be washed immediately.
Patient compliance is vital to successful therapy. Optimal response should be achieved within 14 to 28 days. Continued application 3 to 4 times daily is necessary to sustain its clinical effect.
Availability And Storage: Each tube of cream contains: capsaicin 0.025% in an emollient base. Tubes of 60 g.
ZOSTRIX® Medicis Capsaicin Neuralgia Therapy
Posted by RxMed